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Ergonomic Mice Finder & Comparison Guide

Ergonomic Mouse Finder

Finding the right ergonomic mouse can dramatically improve your comfort, reduce wrist and forearm strain, and help prevent repetitive strain injuries. With so many shapes and features to choose from — vertical, trackball, adjustable, or central bar designs — it can be hard to know where to start.

That’s why we’ve created this simple comparison guide. Explore the table below to discover which ergonomic mouse best suits your hand size, workflow, and posture needs.

Evoluent Right Hand Bluetooth Mouse for Mac

Evoluent Right Hand Bluetooth Mouse for Mac

$237.00

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Oyster Ergonomic Mouse

Oyster Ergonomic Mouse

$217.00

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EZ Vertical Mouse

EZ Vertical Mouse

$107.00

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Evoluent Vertical Mouse 4

Evoluent Vertical Mouse 4

$197.00

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Evoluent Mouse Small

Evoluent Mouse Small

$197.00

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HandShoe Mouse Shift

HandShoe Mouse Shift

$287.00

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RollerMouse Pro3

RollerMouse Pro3

$544.00

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Goldtouch Posture Mouse

Goldtouch Posture Mouse

$97.00

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Unimouse

Unimouse

$219.00

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Kensington SlimBlade Trackball Mouse

Kensington SlimBlade Trackball Mouse

$149.00

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Kensington Orbit Scroll Ring Trackball Mouse

Kensington Orbit Scroll Ring

$97.00

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Kensington Expert Mouse Optical Trackball

Kensington Expert Mouse Optical Trackball

$160.00

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A person's hand holding an ergonomic vertical mouse.

Kensington Expert Mouse Optical Trackball

$207.00

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Logitech MX Ergo Wireless Mouse

Logitech MX Ergo Wireless Mouse

$194.00

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RollerMouse Red

RollerMouse Red

$719.00

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Evoluent Right Hand Bluetooth Mouse for Mac

Evoluent Right Hand Bluetooth Mouse for Mac

$237.00

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Oyster Ergonomic Mouse

Oyster Ergonomic Mouse

$217.00

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EZ Vertical Mouse

EZ Vertical Mouse

$107.00

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Evoluent Vertical Mouse 4

Evoluent Vertical Mouse 4

$197.00

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Evoluent Mouse Small

Evoluent Mouse Small

$197.00

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HandShoe Mouse Shift

HandShoe Mouse Shift

$287.00

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RollerMouse Pro3

RollerMouse Pro3

$544.00

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Goldtouch Posture Mouse

Goldtouch Posture Mouse

$97.00

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Unimouse

Unimouse

$219.00

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Kensington SlimBlade Trackball Mouse

Kensington SlimBlade Trackball Mouse

$149.00

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Kensington Orbit Scroll Ring Trackball Mouse

Kensington Orbit Scroll Ring

$97.00

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Kensington Expert Mouse Optical Trackball

Kensington Expert Mouse Optical Trackball

$160.00

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A person's hand holding an ergonomic vertical mouse.

Kensington Expert Mouse Optical Trackball

$207.00

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Logitech MX Ergo Wireless Mouse

Logitech MX Ergo Wireless Mouse

$194.00

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RollerMouse Red

RollerMouse Red

$719.00

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At a Glance

Wireless ergonomic vertical mouse for Mac users — supports your hand in an upright neutral posture that generally avoids forearm twisting.

One of our bestsellers, the Oyster mouse is fully ergonomic, ambidextrous and adjustable.

A simple, budget-friendly vertical mouse available in both left and right hand orientations.

A major advance in mouse evolution, the Evoluent features a patented shape that will support your hand in a relaxed handshake position, eliminating the arm twisting required by ordinary mice.

The patented shape of the Evoluent, now supporting smaller hands

The Handshoe Mouse Shift is an ambidextrous, dual connectivity mouse, designed with comfort and support front of mind. Available in three sizes.

RollerMouse Pro3 puts mouse controls right at your fingertips so you can type and mouse-around without reaching. Wider roller and larger, easier to click buttons make the Pro the best choice for safer, high speed mousing.

The Goldtouch Computer Mouse is designed to mirror your hand to offer a weightless environment. The unique shape of this ergonomic mouse ensures that your hand is continuously supported and gently tilts your wrist at a 24 degree angle.

Unimouse features a friction-based system for an experience that is simple, yet stable in any position. Effortlessly switch postures on the fly and avoid being locked into one static position.

A low-profile, ambidextrous trackball that lets you control cursor, scrolling and even media by twisting the large, smooth ball, offering precise, all-day comfort with customisable buttons and zero desk movement.

A compact, low-profile trackball that combines mouse-like comfort with precise fingertip control, ideal for smaller hands and tight desks with minimal arm movement required.

A full-size, premium trackball with a large ball and fingertip Scroll Ring® for effortless scrolling, paired with a soft wrist rest for unmatched comfort and exceptional precision.

An ergonomic and ambidextrous vertical mouse that distributes work throughout the fingers, hand, wrist forearm and shoulder.

A premium, adjustable trackball that reduces muscle strain by 20%, lets you tailor the tilt for personalised comfort, and even control multiple computers seamlessly with Logitech FLOW.

A central, rollerbar-controlled mouse that eliminates reaching and gripping, delivering precise fingertip control and up to 20% less forearm effort for pain-free, neutral-position productivity.

Wireless


Available in wired and wireless


Available in wired and wireless


Available in wired and wireless


Available in wired and wireless


Wired and wireless modes


Available in wired and wireless


Available in wired and wireless


Available in wired and wireless

Vertical / Alternative Grip


Vertical


Contoured Ergonomic


Vertical


Vertical


Vertical (smaller size)


Ergonomic shape and enhanced thumb joint support


Alternative bar-style (not standard grip)


High adjustability


Precision grip design allow index finger and thumb work closely together


Alternative bar-style

Trackball


Optical input roller


Large 55mm ball for maximum precision, control and comfort

Adjustable Angle or Tilt


5 different angled positions


Tilts your wrist at a 24 degree angle.


Friction based adjustment with angle of body tilt anywhere between 35-70 degrees.


All controlled by comfort trackball


All controlled by comfort trackball


All controlled by trackball


Adjustable hinge

Compact / Travel Friendly


Wireless version


Wireless version


Wireless version


Wireless version


Wireless version


Wireless version


Wireless version


Wireless version


Wireless version

Programmable Buttons


Only for MacOS 10.5 and earlier

Best For

Mac users wanting ergonomic vertical hold + wireless setup

Long hours, comfort + extra control, general office/design work

Converting from standard mouse to ergonomic, reducing wrist strain

People with hand, wrist or arm pain. People who find the 'handshake' position more comfortable than the standard mouse position (Larger mouse than EZ Vertical)

Petite users / travellers wanting compact ergonomic comfort

Users who dislike traditional shapes, need alternate grip styles.

Graphic designers, heavy typists, those wanting central input & minimal reach

Users wanting neutral wrist posture, avoiding pronation

Users who want maximum ergonomic flexibility, long use/RSI prevention

Users who prefer trackball, less wrist movement, creatives or tight desks

Users with smaller hands, wanting trackball + scroll ring, precision without large motion

Premium trackball experience, CAD/graphic users, long sessions

Users with wrist/forearm discomfort from regular mice, want alternate posture

Users wanting wireless + ergonomic +travel + office combo, comfort without wires

Designers, typists, minimal reach + centralised control area

Recommendations by Need

Vertical grip / wrist strain relief:
Evoluent Right Hand Bluetooth • EZ Vertical • Evoluent Vertical 4

Compact or small hands:
Evoluent Mouse Small • Unimouse

Trackball preference:
Kensington SlimBlade • Orbit Scroll Ring • Expert Mouse

Maximum adjustability / customisation:
Unimouse • HandShoe Mouse Shift • Logitech MX Ergo

Shared input / central bar styles:
RollerMouse Pro3 • RollerMouse Red

Ergonomic Mice FAQs

An ergonomic mouse is designed to reduce strain on your wrist, hand, and forearm. Unlike traditional flat mice, ergonomic models encourage a more natural hand position, which helps prevent repetitive strain injuries (RSI) and improves long-term comfort.

Vertical mice position your hand in a handshake posture, which reduces pronation of the forearm and can relieve wrist tension. If you spend long hours on the computer or already experience wrist pain, a vertical mouse such as the Evoluent series can be a great choice.

Yes — trackball mice minimise wrist and arm movement by allowing you to control the cursor using your fingers or thumb. They’re ideal for users with limited desk space or those who want to reduce repetitive wrist motions. Popular options include the Kensington SlimBlade and Expert Trackball.

If you have smaller hands, choose a compact ergonomic mouse such as the Evoluent Mouse Small or the Unimouse, which are designed with shorter reach and smaller grips to improve comfort and control.

While an ergonomic mouse can’t cure RSI or carpal tunnel syndrome, it can significantly reduce strain and discomfort by improving posture and limiting repetitive stress. For best results, pair it with an ergonomic keyboard and correct desk setup.

Yes — most people need a short adjustment period. For example, a vertical or central bar mouse may feel unusual at first, but after a week or two it typically becomes second nature and much more comfortable than a standard mouse.

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